Protein Purification Services
Comprehensive protein purification and customizable protein analytics packages.
Our protein purification platform is designed for flexibility, scalability, and precision. Whether you’re working with soluble proteins, protein complexes, or membrane-associated targets, we offer tailored workflows to meet your specific needs.
We deliver consistent, reproducible results with fast turnaround using optimized, validated protocols for recombinant protein purification at low milligram to low gram scales. Purification is typically completed in 1-2 weeks as part of a streamlined 8–12 week gene-to-protein workflow.
High-specificity purification using a wide range of affinity tags and ligands. Our affinity purification services are adaptable to your vector design and expression system. Optional tag removal is available through site-specific proteolytic cleavage, using TEV, HRV 3C, SUMO protease and more.
Classical chromatography methods—including ion exchange (IEX), hydrophobic interaction chromatography (HIC), and size exclusion chromatography (SEC)—to separate proteins based on charge, hydrophobicity, and molecular size. These versatile techniques are ideal as polishing steps following affinity purification or can be used as stand-alone purification strategies depending on the biochemical properties of the target protein. Our team can help optimize column selection, buffer systems, and elution conditions to achieve maximum purity and yield
Used to track and verify protein expression, solubility, purity, and concentration throughout the purification workflow, from crude sample to final product.
High-resolution techniques for evaluating molecular weight, homogeneity, and aggregation state of purified proteins. HPLC-SEC enables size-based separation to detect oligomerization or degradation, while intact mass analysis confirms molecular identity and detects post-translational modifications.
Yes, we frequently accept client-supplied starting materials such as cell paste or exhausted culture supernatant. This is a great option if you’ve already completed upstream expression and want to accelerate downstream processing. If protein purification is a bottleneck for your team, we can step in at that stage and provide as much support as needed—from process optimization to scale-up and QC—ensuring a smooth and efficient workflow.
Proteins produced at Proteos are research-grade and are suitable for drug screening, structural biology, and pre-clinical in vivo studies.